Motif Atlas Releases 1.4 and 1.5
Changes in PDB files used for clustering
Release 1.4 has 202 PDB files, release 1.5 has 204 PDB files, 201 of them are identical.
1 equivalence classes changed representatives: 2XZM → 4BPP.
Help Every Motif Atlas release is based on a representative set of PDB files. When comparing two releases, it's important to know how the input data changed.
Representative sets are quite stable in time, but PDB files from the older releases can be replaced by newer PDB files or removed from the set altogether if the structure is obsoleted by PDB without replacement.
PDB files from the newer release either replace representatives in the existing equivalence classes or come from new equivalence classes.
Redistribution of motif instances
Changes in motif groups
Release 1.4 has 271 motif groups, release 1.5 has 274 motif groups, 189 of them are identical.
43 motif groups were updated, 39 groups are present only in release 1.4, 42 groups are only in release 1.5.
Help The Sankey diagram shows redistribution of motif instances (loops) between two releases. The rectangles represent the motif groups and are colored as follows:
Added motif groups: green
Removed motif groups: grey
Updated motif groups: orange
Added motif instances: green
Removed motif instances: grey
Hover over the links connecting the motif groups to see which motif instances were exchanged.
Identical motif groups
# | Motif id | Instances | Description |
---|---|---|---|
1 | IL_56465.3 | 46 | Single, unpaired intercalated base, consensus A |
2 | IL_28947.1 | 21 | 23S H91 IL | cWW-bulge-cWW | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW |
3 | IL_92027.3 | 17 | 16S h21 S8 binding site |
4 | IL_85647.3 | 16 | Sarcin-ricin parent motif with 15 Nts |
5 | IL_43124.1 | 11 | 23S H73 ILa : Part of larger Motif | Single sheared with bulged bases |
6 | IL_02809.2 | 9 | REV element IL with syn G | Tandem cWW pairs (Not AU or GC) |
7 | IL_92114.3 | 9 | GAAA loop receptor "platform" motif |
8 | IL_47444.3 | 9 | SRP Loop E-like motif |
9 | IL_90459.3 | 9 | cWW AG or UU |
10 | IL_73000.2 | 7 | cHS-cWS |
11 | IL_53635.3 | 6 | LSU Helix 32 (H32) IL |
12 | IL_39585.1 | 6 | Double-sheared with two unpaired, stacked As. LSU Helix 68 IL4. |
13 | IL_13069.3 | 6 | LSU 3WJ H32-H33-H35A |
14 | IL_25230.3 | 6 | Bacterial 5S rRNA Loop E |
15 | IL_70237.3 | 6 | |
16 | IL_72158.3 | 6 | LSU Helix 62 (H62) IL |
17 | IL_97057.3 | 6 | |
18 | IL_71288.1 | 5 | Leadzyme Motif. LSU H101 IL2. SSU Decoding site. |
19 | IL_86357.3 | 5 | LSU Helix 61 IL2 |
20 | IL_02359.3 | 5 | |
21 | IL_79083.3 | 5 | |
22 | IL_25300.1 | 5 | 16S h19 IL and 23S H41 IL |
23 | IL_42251.1 | 4 | |
24 | IL_38807.3 | 4 | |
25 | IL_39526.4 | 4 | |
26 | IL_01080.1 | 4 | |
27 | IL_34363.2 | 4 | Kink-turn from 23S H42 |
28 | IL_98591.3 | 4 | |
29 | IL_93568.2 | 4 | Triple Sheared (tSH-tHS-tHS) with wobble cWW. |
30 | IL_22732.1 | 4 | tSH-inserted-tHS |
31 | IL_21333.2 | 4 | tSH-tHW-bulge |
32 | IL_09520.2 | 3 | Leadzyme Motif. SSU Decoding site motif, extended. | cWW-L-cWW-cWW |
33 | IL_80348.1 | 3 | 23S H91 IL |
34 | IL_52173.1 | 3 | |
35 | IL_80494.2 | 3 | LSU H58 IL2 H.m. |
36 | IL_05723.1 | 3 | |
37 | IL_37053.1 | 3 | Kink-turn from 23S H58 |
38 | IL_75447.1 | 3 | |
39 | IL_43946.1 | 3 | |
40 | IL_82563.1 | 3 | Thi-box riboswitch T-loop |
41 | IL_48918.2 | 3 | Kink-turn variant |
42 | IL_34628.2 | 3 | Kink-turn |
43 | IL_79955.2 | 3 | SSU Helix (23) h23 IL1 |
44 | IL_58586.2 | 3 | |
45 | IL_74876.2 | 3 | Double-sheared with two unpaired, stacked As. LSU Helix 68 IL4. |
46 | IL_11751.1 | 2 | |
47 | IL_97833.1 | 2 | |
48 | IL_09348.5 | 2 | Leadzyme Motif. SSU Decoding site motif, extended. | cWW-L-cWW-cWW |
49 | IL_80093.1 | 2 | |
50 | IL_40892.1 | 2 | |
51 | IL_76095.3 | 2 | Motif from Hairpin Ribozyme |
52 | IL_57785.5 | 2 | SSU Decoding Site -- Human. Bulge-cSW-tHS |
53 | IL_94744.1 | 2 | Sarcin-ricin motif with extra cWW GA pair |
54 | IL_50521.1 | 2 | |
55 | IL_12211.1 | 2 | |
56 | IL_00998.1 | 2 | |
57 | IL_69536.1 | 2 | LSU Helix 96 (H96) IL2 |
58 | IL_87548.1 | 2 | |
59 | IL_55287.1 | 2 | |
60 | IL_78744.1 | 2 | Quadruple Sheared (tSH-tSH-tHS-tHS) |
61 | IL_52940.1 | 2 | |
62 | IL_09882.1 | 2 | |
63 | IL_77076.1 | 2 | |
64 | IL_09587.1 | 2 | |
65 | IL_96446.1 | 2 | |
66 | IL_31707.1 | 2 | Vitamin B12 aptamer |
67 | IL_90057.1 | 2 | |
68 | IL_21495.1 | 2 | |
69 | IL_37406.1 | 2 | |
70 | IL_23414.1 | 2 | |
71 | IL_37197.1 | 2 | |
72 | IL_33964.1 | 2 | |
73 | IL_19898.1 | 2 | |
74 | IL_98566.1 | 2 | |
75 | IL_45794.1 | 2 | |
76 | IL_65137.1 | 2 | Kink-turn like motif in Group I Intron |
77 | IL_46435.1 | 2 | |
78 | IL_01054.1 | 2 | |
79 | IL_15840.2 | 2 | Triple Sheared with unpaired, inserted A |
80 | IL_23262.4 | 2 | |
81 | IL_16330.1 | 2 | |
82 | IL_21254.1 | 1 | SSU Helix 11 (h11) IL Kink-turn T. thermophilus |
83 | IL_12507.1 | 1 | |
84 | IL_26868.1 | 1 | |
85 | IL_89794.1 | 1 | |
86 | IL_80652.1 | 1 | |
87 | IL_54450.1 | 1 | |
88 | IL_77014.1 | 1 | |
89 | IL_91078.1 | 1 | |
90 | IL_37347.1 | 1 | |
91 | IL_46306.1 | 1 | |
92 | IL_21421.1 | 1 | |
93 | IL_40527.1 | 1 | Kink-turn |
94 | IL_77296.1 | 1 | |
95 | IL_87394.1 | 1 | |
96 | IL_40845.1 | 1 | |
97 | IL_43316.1 | 1 | |
98 | IL_80505.1 | 1 | |
99 | IL_11302.1 | 1 | |
100 | IL_53988.1 | 1 | |
101 | IL_31754.1 | 1 | Sarcin-ricin H95 23S rRNA E.c. |
102 | IL_71942.1 | 1 | |
103 | IL_06306.1 | 1 | |
104 | IL_05221.1 | 1 | |
105 | IL_06471.1 | 1 | |
106 | IL_91904.1 | 1 | |
107 | IL_58454.1 | 1 | |
108 | IL_41139.1 | 1 | |
109 | IL_03282.1 | 1 | |
110 | IL_42891.1 | 1 | |
111 | IL_85805.1 | 1 | |
112 | IL_92280.1 | 1 | |
113 | IL_57977.1 | 1 | |
114 | IL_82650.1 | 1 | |
115 | IL_66744.1 | 1 | SSU Helix 21 (h21) IL2 E.coli |
116 | IL_27243.1 | 1 | |
117 | IL_75328.1 | 1 | |
118 | IL_83856.1 | 1 | |
119 | IL_53323.1 | 1 | |
120 | IL_26971.1 | 1 | |
121 | IL_09491.1 | 1 | |
122 | IL_64589.1 | 1 | |
123 | IL_91089.1 | 1 | |
124 | IL_94973.1 | 1 | Sarcin-Ricin from Group II Intron with inserted base and poor modeling: |
125 | IL_47732.1 | 1 | |
126 | IL_83250.1 | 1 | 16S h40 3WJ T.th. |
127 | IL_41791.1 | 1 | |
128 | IL_25307.1 | 1 | |
129 | IL_59934.1 | 1 | SSU Helix 23 (h23) Kink-turn E. coli |
130 | IL_52509.1 | 1 | |
131 | IL_61730.1 | 1 | |
132 | IL_81398.1 | 1 | |
133 | IL_98924.1 | 1 | |
134 | IL_59529.1 | 1 | |
135 | IL_02957.1 | 1 | |
136 | IL_82601.1 | 1 | Tandem cWW water-inserted CU pairs |
137 | IL_23448.1 | 1 | |
138 | IL_57285.1 | 1 | |
139 | IL_30354.1 | 1 | |
140 | IL_63952.1 | 1 | |
141 | IL_03110.1 | 1 | |
142 | IL_76263.1 | 1 | |
143 | IL_91379.1 | 1 | |
144 | IL_52958.1 | 1 | |
145 | IL_78809.1 | 1 | |
146 | IL_13682.1 | 1 | |
147 | IL_25082.1 | 1 | |
148 | IL_71685.1 | 1 | Sarcin-like with an intercalated basepair |
149 | IL_25181.1 | 1 | |
150 | IL_17682.1 | 1 | Sarcin-ricin motif from Eukaryal LSU Helix 11 |
151 | IL_60643.1 | 1 | |
152 | IL_46721.1 | 1 | |
153 | IL_86981.1 | 1 | Sarcin-ricin motif with CC BIfurcated pair. H.m. LSU H18. |
154 | IL_68827.1 | 1 | Reverse Kink-Turn |
155 | IL_83920.1 | 1 | |
156 | IL_06468.1 | 1 | 16S h40 3WJ E.c. |
157 | IL_11778.1 | 1 | |
158 | IL_54576.1 | 1 | |
159 | IL_54954.1 | 1 | Sarcin-Ricin with extra tSH UA basepair. Yeast LSU H11. |
160 | IL_23639.1 | 1 | tWH-tHS-L-cWW |
161 | IL_15205.1 | 1 | |
162 | IL_91044.1 | 1 | |
163 | IL_27668.1 | 1 | |
164 | IL_88865.1 | 1 | |
165 | IL_39324.1 | 1 | |
166 | IL_86059.1 | 1 | |
167 | IL_97191.1 | 1 | Sarcin-ricin motif with cWW UU instead of tSH basepair. |
168 | IL_47687.1 | 1 | |
169 | IL_31006.1 | 1 | tSH-tHW-L-bif-cWW |
170 | IL_55649.1 | 1 | |
171 | IL_20775.1 | 1 | tSH-inserted |
172 | IL_75415.1 | 1 | Pseudo-knot forming internal loop |
173 | IL_76486.1 | 1 | Sarcin-ricin motif with syn G |
174 | IL_37990.1 | 1 | |
175 | IL_17603.1 | 1 | |
176 | IL_85510.1 | 1 | |
177 | IL_06847.1 | 1 | Group II Intron IL |
178 | IL_30067.1 | 1 | |
179 | IL_09333.1 | 1 | SSU Helix 8 (h8) IL T. thermophilus |
180 | IL_02835.1 | 1 | |
181 | IL_28644.1 | 1 | |
182 | IL_06808.1 | 1 | Double sheared (tSH-tSH) one bulged base. |
183 | IL_03741.1 | 1 | |
184 | IL_97842.1 | 1 | |
185 | IL_98655.1 | 1 | Part of H71 Junction in 26S rRNA from Yeast |
186 | IL_56513.1 | 1 | |
187 | IL_88367.1 | 1 | |
188 | IL_60649.1 | 1 | Kink-turn |
189 | IL_52610.1 | 1 |
Updated motif groups
# | Motif id | Instances | Description |
---|---|---|---|
1 | IL_97217.7 | 243 | 1-3 bulged nucleotides, same chain | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW |
2 | IL_47174.8 | 205 | cWW AG or water inserted cWW Y-Y. |
3 | IL_39199.4 | 53 | Hoogsteen-edge Platform, Single bulged base |
4 | IL_41766.4 | 49 | Tandem cWW pairs (Not AU or GC) |
5 | IL_44540.4 | 43 | Sugar-edge, 1-base platform, consensus tHS |
6 | IL_87904.5 | 31 | Triple sheared (tSH-tHS-tHS) no inserted bases |
7 | IL_13959.4 | 26 | Double Sheared (tSH-tHS) |
8 | IL_65553.6 | 22 | Kink-turn |
9 | IL_93424.4 | 21 | tSH-inserted-tHW |
10 | IL_73276.4 | 21 | C-loop |
11 | IL_55938.4 | 18 | LSU Helix 89 (H89) IL2. cSH Platform. |
12 | IL_94430.5 | 16 | 16S h32-h33-h34 3WJ |
13 | IL_24982.5 | 16 | SSU helix 20 (h20) IL. Prokaryal 5S Loop E Sub-motif |
14 | IL_92109.2 | 15 | cWW-bulge-cWW | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW |
15 | IL_49493.4 | 13 | Sarcin-ricin Parent Motif - bacterial LSU H95 IL |
16 | IL_31555.4 | 13 | Tandem sheared with inserted, unpaired purine. |
17 | IL_46648.3 | 10 | 23S H91 IL | Single-Base Intercalation Site |
18 | IL_40090.5 | 10 | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) | 16S h34 ILa : Part of larger motif |
19 | IL_24546.4 | 10 | 23S H41 IL and 16S h18 IL : Has large bulge on one side |
20 | IL_58291.4 | 10 | Recurrent Sub-motif found in junctions |
21 | IL_83451.3 | 7 | cHS-cWS triple and Wobble. SSU Helix 44 (h44) IL1. |
22 | IL_92321.4 | 7 | Triple sheared (tSH-tHS-tHS) with cWW Wobble base flanking motif |
23 | IL_90133.3 | 6 | |
24 | IL_77263.2 | 6 | Kink-turn from U4 |
25 | IL_08926.3 | 6 | 23S H91 IL |
26 | IL_44067.4 | 5 | Quadruple sheared (tSH-tHS-tHS-tHS). LSU Helix 2 (H2). |
27 | IL_95652.3 | 4 | SSU Helix 27 (h27) IL Sarcin-Ricin motif |
28 | IL_71565.4 | 4 | |
29 | IL_47758.2 | 4 | REV element IL with syn G | Tandem cWW pairs (Not AU or GC) |
30 | IL_31066.3 | 4 | SSU Helix 44 (h44) extension |
31 | IL_45262.4 | 4 | |
32 | IL_28572.2 | 4 | 16S h18 kink-turn like motif |
33 | IL_82188.2 | 4 | LSU H68 IL from H.m. |
34 | IL_94403.2 | 3 | LSU H77 |
35 | IL_25271.2 | 3 | SSU Helix 8 (h8) IL E.c. and Yeast |
36 | IL_98421.4 | 3 | SSU Helix 12 (h12) IL |
37 | IL_62499.7 | 3 | |
38 | IL_89028.6 | 3 | Part of Helix 71 (H71) junction in 23S rRNA E.c. H.m. and Tetrahymena | Part of H71 junction in 23S rRNA from T.th. |
39 | IL_16166.4 | 3 | 23S H91 IL |
40 | IL_30840.2 | 3 | |
41 | IL_07300.2 | 3 | |
42 | IL_95150.4 | 3 | |
43 | IL_16415.2 | 3 | SSU Helix 23 (h23) Kink-turn T. thermophilus |
Removed motif groups
# | Motif id | Instances | Description |
---|---|---|---|
1 | IL_06390.3 | 26 | cWH basepair with syn base |
2 | IL_21304.2 | 11 | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) |
3 | IL_54420.1 | 6 | |
4 | IL_78732.3 | 5 | Double S-turn motif |
5 | IL_16207.1 | 5 | Single sheared with bulged bases |
6 | IL_92484.1 | 5 | |
7 | IL_08559.1 | 4 | LSU Helix 89 (H89) IL2 |
8 | IL_34156.6 | 3 | cWW AG or UU |
9 | IL_10647.1 | 3 | tHS tHH bulge with S-turn |
10 | IL_56077.1 | 3 | |
11 | IL_92267.1 | 3 | 23S H73 ILa : Part of larger Motif |
12 | IL_09901.1 | 2 | tHS tHH bulge with S-turn |
13 | IL_70280.1 | 2 | Double sheared with wobble cWW. |
14 | IL_24358.1 | 2 | |
15 | IL_27892.1 | 2 | |
16 | IL_49550.1 | 2 | tHS tHH bulge with S-turn |
17 | IL_88180.1 | 2 | cWW-bulge-cWW |
18 | IL_28942.1 | 2 | |
19 | IL_91273.1 | 2 | |
20 | IL_16252.3 | 2 | 23S H91 IL |
21 | IL_33925.1 | 2 | |
22 | IL_21221.1 | 1 | SSU Helix 12 (h12) IL |
23 | IL_67735.1 | 1 | |
24 | IL_95774.1 | 1 | tHS tHH bulge with S-turn |
25 | IL_34868.1 | 1 | LSU Eukaryal Helix 96 (H96) IL1 |
26 | IL_97073.1 | 1 | |
27 | IL_37715.1 | 1 | |
28 | IL_02690.1 | 1 | |
29 | IL_12486.1 | 1 | |
30 | IL_41341.1 | 1 | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) |
31 | IL_82113.1 | 1 | |
32 | IL_03931.1 | 1 | 16S h19 IL and 23S H41 IL |
33 | IL_13434.1 | 1 | |
34 | IL_28468.1 | 1 | Single sheared with bulged bases |
35 | IL_04550.1 | 1 | tHS tHH bulge with S-turn |
36 | IL_15674.1 | 1 | Part of Helix 71 (H71) junction in 23S rRNA E.c. H.m. and Tetrahymena | Part of H71 junction in 23S rRNA from T.th. |
37 | IL_05462.1 | 1 | |
38 | IL_31290.1 | 1 | |
39 | IL_65788.1 | 1 |
Added motif groups
# | Motif id | Instances | Description |
---|---|---|---|
1 | IL_82444.1 | 29 | cWH basepair with syn base | cWW AG or water inserted cWW Y-Y. | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) | 16S h34 ILa : Part of larger motif |
2 | IL_37104.1 | 11 | Single sheared with bulged bases | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) |
3 | IL_25380.1 | 6 | LSU Helix 89 (H89) IL2 |
4 | IL_05684.1 | 5 | tHS tHH bulge with S-turn | Double S-turn motif |
5 | IL_09530.1 | 4 | Double S-turn motif |
6 | IL_15768.1 | 4 | cWW AG or UU | cWH basepair with syn base |
7 | IL_31663.1 | 4 | 23S H73 ILa : Part of larger Motif |
8 | IL_39980.1 | 4 | |
9 | IL_87065.1 | 3 | 23S H91 IL | Single-Base Intercalation Site |
10 | IL_06180.1 | 3 | tHS tHH bulge with S-turn |
11 | IL_06211.1 | 3 | |
12 | IL_30381.1 | 2 | tHS tHH bulge with S-turn |
13 | IL_46034.1 | 2 | |
14 | IL_12685.1 | 2 | cWW AG or UU | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) |
15 | IL_96206.1 | 2 | |
16 | IL_97509.1 | 2 | Double sheared with wobble cWW. |
17 | IL_35595.1 | 2 | 23S H73 ILa : Part of larger Motif | Single sheared with bulged bases |
18 | IL_35994.1 | 2 | cWW-bulge-cWW | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW |
19 | IL_87507.1 | 2 | tHS tHH bulge with S-turn |
20 | IL_21639.1 | 2 | |
21 | IL_39355.1 | 2 | SSU Helix 12 (h12) IL | LSU Eukaryal Helix 96 (H96) IL1 |
22 | IL_67887.1 | 2 | |
23 | IL_90735.1 | 2 | |
24 | IL_68767.1 | 1 | |
25 | IL_96182.1 | 1 | cWH basepair with syn base |
26 | IL_31224.1 | 1 | 23S H91 IL |
27 | IL_49527.1 | 1 | |
28 | IL_69799.1 | 1 | |
29 | IL_02897.1 | 1 | Part of Helix 71 (H71) junction in 23S rRNA E.c. H.m. and Tetrahymena | Part of H71 junction in 23S rRNA from T.th. |
30 | IL_49976.1 | 1 | |
31 | IL_18675.1 | 1 | cWW-bulge-cWW |
32 | IL_50911.1 | 1 | 16S h34 ILa : Part of larger motif |
33 | IL_99438.1 | 1 | |
34 | IL_06177.1 | 1 | cWW AG or UU |
35 | IL_20530.1 | 1 | |
36 | IL_54470.1 | 1 | tHS tHH bulge with S-turn |
37 | IL_21077.1 | 1 | |
38 | IL_57364.1 | 1 | LSU Helix 89 (H89) IL2 |
39 | IL_87523.1 | 1 | |
40 | IL_59018.1 | 1 | |
41 | IL_88119.1 | 1 | |
42 | IL_06421.1 | 1 | Single sheared with bulged bases |